Study of the Blood Oxygen Level Dependent (BOLD) response in spinal fMRI.
Maugeri L., Mangini F., Moraschi M., Mascali D., Cedola A., Giove F., Fratini M.
V - Biofisica e fisica medica
Aula 32C-2 - Mercoledì 19 h 09:00 - 13:00
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Functional MRI (fMRI) is a powerful tool for the investigation of the central nervous system. Despite some recent progress, however, many issues still need to be solved for spinal cord fMRI to be used for clinical applications. Recently, we have been developing new strategies for studying the exact features and the biophysical origins of the spinal cord fMRI response in healthy and diseased subjects. These strategies are based on innovative acquisition and data analysis protocols, aiming at a dramatic reduction of physiological noise (due to cardiac pulse and respiration). Italian Ministry of Health (Grant2013:GR-2013-02358177) is acknowledged for financial support.