IRBIS (Ionizing Radiation exposure of Blood Samples) project: An innovative interdisciplinary approach of biological dosimetry to investigate blood and cell samples exposed to radon.
Guida M., Falanga M.R., Mancini S., Ismail A.H., Turco M.C., Pilotti I.
V - Biofisica e fisica medica
Aula 32C-2 - Mercoledì 19 h 09:00 - 13:00
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The project deals with an innovative approach for investigating biological effects on in vitro human blood and cell samples, exposed to low-dose high LET alpha radiation from radon, involving skills from medical physics, biology and radioprotection. According to IARC-WHO, exposure to radon can cause cancers and blood pathologies. To better design prevention actions protecting people, advanced In vitro investigations are needed for understanding the early changes induced by radiation at cellular level. This frontier research can spread light on biological mechanisms of cancer, knowledge fundamental for health protection and therapies for cancer patients, through the biomarkers identification for early disease detection.