Lipid bilayer adhesion from molecular scale interactions to synergy and antagony at macroscopic contacts.
Bilotto P., Lengauer M., Mears L., Valtiner M.
V - Biofisica e fisica medica
Aula 32C-2 - Lunedì 17 h 16:00 - 19:00
» Download abstract
Understanding how many molecules ($\approx$107) interact across an adhesive contact, and how specific molecules can have synergistic and antagonistic effects, can advance our comprehension of adhesion at solid liquid interfaces. We utilize lipid bilayers as a versatile model system to easily cause interface modifications, increasing the complexity of the system. We evaluate adhesive interaction using a Surface Force Apparatus and atomic force microscope to investigate the short distance force and energy landscapes of interacting entities. We will present results from confinement of the lipid bilayer and an initial increase in complexity with controlled number densities of polymers at interface.