# Exploring the response to acute photon exposure of Drosophila melanogaster grown at different low dose rates starting from the reduced natural background radiation at the LNGS Laboratory

Morciano P., Ianni A., Balata M., Cipressa F., Porrazzo A., De Gregorio A., Esposito G., Alesse E., Cenci G., Tabocchini M.A.

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V - Biofisica e fisica medica
GSSI Ex ISEF - Aula B - Giovedì 26 h 09:00 - 12:30
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Systematically studying the dependence of the priming dose rate on the D. melanogaster adaptive response, we found that exposure to 40 cGy at 2.5 mGy/h induces a $\sim 50$% reduction of chromosome breaks with respect to the control flies directly exposed to 10 Gy. However, this phenomenon is not linearly related with the dose/dose rate. We are presently extending our investigation keeping flies inside the INFN-LNGS underground laboratory. Preliminary data suggest that after irradiation with 10 Gy flies grown underground for two generations at extremely low dose rate show a similar chromosome damage as those kept in reference radiation environment.

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