Measuring metabolism across scales.

Metabolism is a complex and interconnected process that involves numerous biochemical reactions and pathways, transforming energy from one form to another and regulating nutrient intake to maintain the living state of cells and organisms. To study metabolic physiology, we need to consider dynamic processes that occur over different scales of time and space. Investigating the connection between metabolism and diseases requires a multifaceted approach that examines how metabolism integrates with molecules, organelles, cells, tissues, and organisms. Therefore, measuring, mapping, and integrating metabolism across various scales and systems is crucial to comprehending human physiology and finding treatments for various diseases. The combination of Metabolic Imaging and Metabolic Modeling techniques allow to understand holistically the metabolism of living systems, from cells to organisms, relying on the latest technological advances in artificial intelligence and microscopy in order to unlock the mysteries behind metabolic processes.