A magnetic resonance imaging study of graphene oxide.

Alecci M. , Fioravanti G., Galante A. , De Thomasis G., Perrozzi F., Florio T.M., Colacicchi S., Profeta G. , Ottaviano L.

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Magnetic Resonance Imaging (MRI) is a powerful clinical diagnostic tool and its domain is currently developing towards molecular imaging suitable for animal models of disease. Graphene oxide (GO), obtained by the Hummers method, seems an interesting structure to be used as MRI contrast agent to improve specificity and/or sensitivity. In this 2.35 T MRI study we characterized the longitudinal and transverse relaxation times of GO water solutions at various concentrations. EPR spectra at X band allowed to confirm the presence of $Mn^{2+}$ ions anchored to the graphene oxide planes and radical-like carbon-inherited defects, both contributing to the NMR water relaxation mechanisms.

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